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ROBYN ST. LAURENT, PHD

Neuroscientist interested in uncovering brain circuit mechanisms of substance abuse disorder and psychiatric illness.

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MY RESEARCH INTERESTS AND BACKGROUND

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I am interested in understanding the neural circuit control of behaviors that are disrupted in psychiatric disorders and substance abuse. I am particularly interested in how neuromodulators impact inhibitory synapses in the brain.  My research focuses on identifying the maladaptive changes to neural circuitry that underlies psychiatric disease in an effort to provide new avenues for therapeutic interventions.

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I started my scientific journey as an undergraduate (at Colby College) and post-baccalaureate trainee (at NIDA) where I focused on the neural circuitry involved in drugs of abuse. From there, I became an experienced slice electrophysiologist during my PhD (at Brown) and uncovered circuit specific synaptic plasticity that was differentially regulated by opioids.

 

Currently, as a postdoctoral scholar (at Stanford), I study amygdala circuits that are involved in  negative reinforcement and opioid use disorder. We linked amygdala dysfunction in a particular subregion with behavioral, neuronal and synaptic impairments in a mouse model of obsessive-compulsive disorder. Then, we identified an intervention that rescued behavioral deficits in Sapap3 knockout mice during a task that is relevant to exposure response therapy. 

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ACADEMIC EXPERIENCE

EDUCATION & TRAINING

BACHELOR OF ARTS, COLBY COLLEGE

2008 - 2012

Graduated cum laude in Psychology w/Neuroscience concentration

Worked in labs of Drs. Steven Harrison, Tariq Ahmad, Melissa Glenn

Postbaccalaureate Intramural Research Training Award
National Institute on Drug Abuse

Behavioral Neuroscience Branch
Mentor: Yavin Shaham, PhD

 

2012 - 2014

DOCTOR OF PHILOSOPHY

BROWN UNIVERSITY

2014 - 2019

POSTDOCTORAL SCHOLAR 
GLADSTONE INSTITUTES & UCSF

2019 - 2022*

POSTDOCTORAL SCHOLAR
STANFORD UNIVERSITY

2022 - present

Department of Neuroscience
Degree Conferred: May 2019 
Link to my dissertation
Mentor: Julie Kauer, PhD
Committee: Drs. Barry Connors, Christopher Moore, Christopher McBain

Department of Neurological Disease

Mentor: Anatol Kreitzer, PhD

*Kreitzer Lab closed August 2022

Department of Psychiatry and Behavioral Sciences

Mentor: Robert Malenka, MD PhD 

TECHNICAL EXPERTISE

SLICE ELECTROPHYSIOLOGY

COMPLEX BEHAVIOR

COMPUTATIONAL ANALYSIS

DRUG SELF ADMINISTRATION

OPTOGENETICS,
CHEMOGENETICS

FIBER PHOTOMETRY

ANATOMY

MY SKILL SET

Being a scientist requires more than technical prowess, novel ideas, and attention to detail...I strive to always be a good colleague, mentor, and member of the community. Below are some attributes that I highly value and believe are essential to being a great scientist and leader.

MENTORING

I have formally and informally mentored others at every stage of my scientific journey. Early on, this took the form of teaching others how to do something, like rodent surgery. Now, I have more experiences acting as a primary mentor for undergraduates. Inclusion is a cornerstone of this part of my job. Mentoring is not only a skill, but a passion of mine that I look forward to improving on.

DIVERSITY, EQUITY & INCLUSION / OUTREACH

A major motivating factor in my career has been to improve equity and access to scientific careers for underrepresented groups.  I consider it both my duty and privilege as a scientist to make STEM more inclusive for everyone and will continue to champion DEI efforts as a member of the scientific community.

SCIENCE COMMUNICATION

Dissemination of research findings is critical for scientific progress as well as building trust with the wider community. I pride myself on my ability to communicate my ideas and findings to anyone, tailoring the words to make the conversation, publication, or presentation understood by those present.

PROJECT MANAGEMENT

If you know me, you'll know that I love to juggle at least a few projects at once. Maybe it's that science is full of failures and it's nice to always have something on the back-burner or maybe I just can't pick only one question at a time. Either way, I've developed copious skills in managing my time, keeping others on track, and making sure that we move forward efficiently.

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MORE ABOUT ME

CHECK OUT MY LATEST WORK!

Intercalated amygdala dysfunction drives avoidance extinction deficits in the Sapap3 mouse model of obsessive-compulsive disorder

IN THE NEWS:
Selected as Philadelphia SPINE Fellow

Symposium for Postdoctoral Initiatives in Neuroscience Excellence

IN THE NEWS

Trailblazing Trainee Award

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Neural underpinnings of ketamine treatment in obsessive-compulsive disorder

IN THE NEWS

Brown Alumni Spotlight

IN THE NEWS

Berkelhammer Award

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